A salient component of the mission of Stranaska Scientific is to educate FDA-regulated laboratories in analytical spectrophotometric metrology so that their UV/VIS measurement results will have credibility, validity and scientific defensibility. This can easily be achieved in part by realizing the critical need to expose and eliminate out-dated commercial calibration methodologies that still remain unchallenged in practice which contribute to poorly “calibrated” filters with “certified” calibration results that have no scientific validity and defensibility. FDA-regulated laboratories that do not recognize such unscrupulous calibration practices place themselves at unnecessary risk by jeopardizing the scientific validity and defensibility of their spectrophotometer AIQ and measurement results. Here you will learn how to easily recognize the most critical risk factors when selecting your next commercial UV/VIS calibration company or corporate metrology laboratory.

Considerations for out-sourcing the qualification of analytical UV/VIS absorption spectrophotometers and microplate readers.

  1. Always verify the scientific metrological credentials of the calibration technician that will perform the qualification procedures. Has the technician been formally trained and received education in analytical UV/VIS spectrophotometric metrology?
  2. Always verify that the qualification includes the four (4) fundamental parameters reference by USP: resolution (spectral bandwidth), stray light, wavelength scale accuracy and photometric scale accuracy.
  3. Always verify the scientific metrological validity of the calibration filters that will be used in the qualification procedures. Have the filters been certified by a commercial laboratory that has NIST heritage? Does the commercial laboratory have the scientific metrological expertise to know to provide multiple options of photometric calibrations?
  4. Always review the report or certificate provided for the recertification of the calibration filters. Does the report or calibration clearly identify presumptive out-of-tolerances that may occur with as-received measurements?

REMEMBER that low-bid quotations generally do not satisfy the criteria of the four (4) important considerations listed above.

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